CD206 is a marker of TAMs and correlated as an inhibitor of antitumor immune response36 and a poor prognostic marker of cancer.37 We observed a significantly lower level of CD206 in surviving cells after polarized M2-like macrophages were treated with PD-L1 BiTEs both in NS media and in the presence of ascites fluids (figure 6C). This evidence concerns the gene MRC1 and cancer.