Between the TGF-β family co-receptors (ENG and TGFBR3) implicated in cancer progression and inhibin function, ENG was more expressed (Fig 1c), particularly in lung adenocarcinoma and gastric cancers, corresponding with ENG being a strong negative predictor of survival (Figs 1c and 2). This evidence concerns the gene TGFB1 and gastric cancer.