To begin to evaluate the impact of this relationship more broadly in cancers we analyzed gene alterations including mutations, amplifications, and deletions for the genes encoding inhibin/activin subunits (Fig 1a) INHA, INHBA, INHBB, and the key coreceptors—TGFBR3, and ENG in all public datasets available in cBioPortal (Fig 1b, S1 Table). This evidence concerns the gene INHA and cancer.