TREM2 and Alzheimer disease: Expression of the synaptic functional markers dynamin 1 and PSD95 differed (Figure 4B; p < 0.05), while the AD biomarkers Tau, p-Tau, APOE, CD33, and TREM2 showed no obvious differences in expression (Figure 4D; p > 0.05), except for Aβ42 (Figure 4B, p = 0.0001).