Subsequently, we also confirmed the expression of PRDX2 in colorectal cancer using a large number of colorectal cancer tissue samples (226 cases), and PRDX2 overexpression was identified an independent and unfavorable prognostic indicator in stage I-III, early stage (stage I-II) and advanced stage (stage III) colon cancer patients [41]. Here, PRDX2 is linked to colorectal cancer.