For example, the mitogen-activated protein kinases (ERK pathway) control cell proliferation, Aurora B plays a pivotal role in cell division of the G2/M phase, and BRAF/ERK axis controls Aurora B expression at the transcriptional level, likely through the transcription factor, Fork head box M1 (FOXM1) in melanoma cells (Bonet et al. 2012). The gene discussed is AURKB; the disease is melanoma.