ESR1 and uterine corpus leiomyoma: Recently, Cd has been proposed to act as an environmental endocrine disruptor (Gao et al. 2015; Johnson et al. 2003; Kluxen et al. 2012), or an estrogen “mimic” in the rat uterus (Johnson et al. 2003), and Cd blood concentrations correlate with estrogen receptor levels in women with uterine fibroids (Nasiadek et al. 2011; Ye et al. 2017).