CMTM6 expression in TCs and ICs was positively correlated with CD68+ macrophage density (r = 0.200, P = 0.028 and r = 0.222, P = 0.015, respectively) and CD163+ M2 macrophage density (r = 0.095, P = 0.026 and r = 0.292, P = 0.001, respectively) in dMMR CRC but not in pMMR CRC (Table 1). This evidence concerns the gene CMTM6 and colorectal carcinoma.