Analysis of the correlations of the expression levels of CMTM6 and PD-L1 and the densities of ICs with clinicopathological parameters showed that the expression level of CMTM6 in TCs was related to tumor size in dMMR CRC (P = 0.028), and there was no correlation between the expression level of CMTM6 in TCs or ICs and any other clinical parameters in dMMR CRC and pMMR CRC. This evidence concerns the gene CD274 and colorectal carcinoma.