Fifteen genes (KMO, RPS27A, SPNS2, TUBA1B, BASP1, FBRSL1, AATK, PLK5, LRRC75A, TLCD4, IP6K3, DPY19L2P2, LRRN2, BTLA, and ALOX15) in opposite model significantly differentially expressed in patients with sepsis and ARDS compared to those with sepsis alone. This evidence concerns the gene BTLA and acute respiratory distress syndrome.