To select significant features of sepsis with ARDS, features were detected in ‘train’ set with SVM-RFE method using 194 genes (160 in the opposite model and 34 in the specific model) and validated with the ‘test’ set; the model of 3 genes (TLCD4, PRSS30P, and ZNF493) and seven genes (TLCD4, PRSS30P, ZNF493, AGO2, SLC37A3, SLC2A1, and RPL11) showed moderate performance in the ‘test’ group with AUC of 0.67 (Figure 6b). This evidence concerns the gene TLCD4 and acute respiratory distress syndrome.