TLCD4 and Sepsis: To select significant features of sepsis with ARDS, features were detected in ‘train’ set with SVM-RFE method using 194 genes (160 in the opposite model and 34 in the specific model) and validated with the ‘test’ set; the model of 3 genes (TLCD4, PRSS30P, and ZNF493) and seven genes (TLCD4, PRSS30P, ZNF493, AGO2, SLC37A3, SLC2A1, and RPL11) showed moderate performance in the ‘test’ group with AUC of 0.67 (Figure 6b).