We also employed a different set of KRAS‐wt and KRAS‐mt mouse organoids (Apc−/−Trp53−/−Kraswt and Apc−/−Trp53−/−KrasG12D) as these co‐occurring mutations are predominant in colorectal cancer and thought to be more biologically relevant. This evidence concerns the gene APC and colorectal cancer.