In ovarian cancer (OCa), the NaV1.5 isoform appears to be the main NaVα subunit expressed and contributing to the migration and invasion capabilities of cancer cells (Gao et al., 2010; Liu et al., 2018); however, the splicing status of NaV1.5 in this carcinoma is currently unknown. The gene discussed is SCN5A; the disease is ovarian cancer.