PDK2 and hepatocellular carcinoma: The overexpression of miR-1287 in the PDK2 WT group notably decreased the luciferase activity compared with the miR-NC group and the PDK2 WT group, and the transfection of miR-1287 or miR-NC in the PDK2 MUT group had no influence on the luciferase activity (Figure 5b and c), suggesting the interaction between miR-1287 and PDK2 in HCC cells.