To further explore the role of the regulatory networks of TRAF3 and miR-339-3p in AP, we treated AR42J cells with 100 nM caerulein to construct an AP model, and miR-339-3p, NC, miR-399-3p + vector, and miR-339-3p + TRAF3 were transfected into these cells and divided into 100 nM caerulein + miR-339-3p, 100 nM caerulein + NC, 100 nM caerulein + miR-339-3p + vector, and 100 nM caerulein + miR-339-3p + TRAF3 groups. Here, TRAF3 is linked to alkaline phosphatase measurement.