XIAP and acute myeloid leukemia: Shang’s team identified 49 circRNAs that were differentially expressed in DXR-resistant and sensitive THP-1 acute myeloid leukemia cell lines, and among them, circPAN3 knockdown could sensitize resistant THP-1 cells to DXR through the miR-153-5p/miR-183-5p-XIAP axis [27].