Guan et al. [12] explored the relationship between fibrinogen and epidermal growth factor receptor (EGFR) mutation status in patients with NSCLC; they found that plasma fibrinogen levels were distinctly higher in patients with wild-type EGFR gene than in patients with EGFR mutations (3.57 g/L vs 2.95 g/L, p < 0.001). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.