But the expression difference of FXYD6 mRNA and proteinbetween normal liver tissue and cirrhosis was not obvious, indicating that the FXYD6protein might not participate in the process of transforming normal liver tissue intocirrhosis with HBV infection, but acted as an essential factor of the hepatocellularcarcinogenesis in cirrhosis. This evidence concerns the gene FXYD6 and Cirrhosis.