The results showed that plasma levels of endotoxin, homocysteine, ALT, AST, TB, TC, and TG were significantly higher than the normal control group (P < 0.05), indicating that the compound pathogenic factors induced IETM in the rat models, with severely impaired liver cells, aggregation of liver lipids, metabolic disorders, and hyperhomocysteinaemia. The gene discussed is GPT; the disease is Other metabolic disease.