LBHD1 and urinary bladder cancer: Overexpression of LBHD1 increased the protein expression of LBHD1 at least 500-fold (Fig. 3A) In contrast to the siRNA knockdown of LBHD1 in BLZ-211 cells that induced cell migration and invasion repression, overexpression of LBHD1 increased cell migration by 200-319% and increased invasion in 253J human bladder cancer cells (Fig. 3B and 3C)