Knockdown of LBHD1 with siRNA decreased 67-75% of cell migration and invasion in BLZ-211 bladder cancer cells (Fig. 2B and Fig. 2C) These results suggested that LBHD1 might be involved in the migration and invasion of BLZ-211 cells and that LBHD1 siRNA negatively affected these behaviors. The gene discussed is LBHD1; the disease is urinary bladder carcinoma.