MMP9 and carcinoma: In addition, the tissue MMP-9 level is a prognostic factor for poor clinical outcomes in patients with various carcinomas, including hepatic breast cancer metastases, prostate cancer, salivary adenoid cystic carcinoma, and gastric cancer [7, 11, 12, 13], because its level is typically associated with recurrence, advanced clinical stage, presence of invasion or metastasis, and shorter survival time.