Currently, a phase 1 study for Systemic Sclerosis patients with human anti-TGF-β1 monoclonal antibody started in 2002 (ClinicalTrials.gov NCT00043706), but no results have been published, and no clinical trials have described the role of TGF-β1-related drugs in uveitis. This evidence concerns the gene TGFB1 and systemic sclerosis.