ACTG1 and cancer: Subsequently, predicted target genes were subjected to KEGG pathway analysis, and the results revealed some important cancer and stem-related pathways including the HIPPO signaling pathway, TGFb signaling pathway, and Wnt signaling pathway (Figure 7(a)), in which 4 genes (ACTG1, CSNK1D, PPP1CC, and BIRC5) were clustered in the HIPPO signaling pathway.