Four out of six ARVC patients (patients 4, 5, 7, 9) carried genetic variants in genes (PKP2, DSG2, and JUP) coding for desmosomal proteins—plakophilin-2, desmoglein-2, and junctional plakoglobin. The gene discussed is DSG2; the disease is arrhythmogenic right ventricular cardiomyopathy.