KLF6 and neoplasm: In the course of studying the mechanism of KLF6-SV1 and tumor migration, we unintentionally found that KLF6-SV1 is closely related to a variety of EMT-activated transcription factors, and that the effect of KLF6-SV1 on tumor invasion and migration is likely to be mediated by the regulation of EMT (Figure 4B).