For example, HOXA1 gene expression level is reported to enhance proliferation and metastasis in prostate cancer (Wang et al., 2015), breast cancer (Liu J. et al., 2019), and gastric cancer (Yuan C. et al., 2016) and predict poor prognosis in non-small-cell carcinoma (Zhang Y. et al., 2018). This evidence concerns the gene HOXA1 and Familial prostate cancer.