It is, therefore, hard to envisage a role for STARD3 as an LTP that enriches DMVs with endosomal sterol, and a recent study screening a CRISPR library for proteins required for SARS-CoV-2 infection found that neither endosomal STARD3 nor one of its ER-localized binding partners, MOSPD2 (Di Mattia et al., 2018), mediates viral infection or virus-induced cell death (Schneider et al., 2020). The gene discussed is STARD3; the disease is viral infectious disease.