TGFBI and Thiel-Behnke corneal dystrophy: For instance, according to the second edition of IC3D, five distinct TGFBI mutations (p.R124H, p.R555W, p.R124C, p.R555Q, and p.R124L) cause different types of CDs, including Granular corneal dystrophy, type 2; Granular corneal dystrophy, type 1; Lattice corneal dystrophy, type 1 (LCD1); Thiel-Behnke corneal dystrophy (TBCD); and Reis-Bücklers corneal dystrophy, respectively, (Weiss et al., 2008, 2015).