Fifty-one patients with TGFBI corneal dystrophy were detected, including 8 patients with p.R124C, 18 patients with p.R124H (15 patients with heterozygous mutations and 3 patients with homozygous mutations), 2 patients with p.R124L, 1 patient with p.T538R, 11 patients with p.R555W, 6 patients with p.R555Q, 2 patients with p.L565H, and 3 patients with p.H626R. The gene discussed is TGFBI; the disease is corneal dystrophy.