These toxins differ in their virulence and host specificity (Fuller et al., 2011; Lee and Tesh, 2019; Petro et al., 2019) with Stx2 being most commonly associated with severe illness (HUS, hospitalization, and bloody diarrhea) in humans (Karmali et al., 1983; Panel et al., 2020). Here, STX2 is linked to hemolytic-uremic syndrome.