In year 1, the prevalence of stx1 in contents was higher (P = 0.001, Table 2) in AN (n=18; 78%) compared to CH (n=7; 35%) and KC (n=6; 27%), and the prevalence of stx2 was higher (P < 0.001, Table 2) in AN (n=22; 96%) and CH (n=20; 100%) than in KC (n=4; 18%). The gene discussed is STX2; the disease is keratoconus.