In Figures 3C, D, the protein expression levels of ICAM-1 (YM:0.61 ± 0.20 vs. YC:0.39 ± 0.05, P<0.01; OM: 0.67 ± 0.20 vs. OC:0.47 ± 0.08, P<0.05) and VCAM-1 (YM:0.37 ± 0.11 vs. YC:0.12 ± 0.04, P<0.01; OM: 0.15 ± 0.02 vs. OC:0.12 ± 0.04, P<0.01) in the aorta were both significantly higher in the YM and OM groups than those in the YC and OC groups. This evidence concerns the gene VCAM1 and ocular melanoma.