Serum levels of pro-inflammatory cytokines include GM-CSF, MCP-1, TNF-α, CD40L, KC and IL-13, and were significantly higher in the OM group than those in the YM group (Figures 2A, G–I, K, N), while the level of IL-10 was lower in the OM group compared to that in the YM group (Figure 2M). Here, CALCA is linked to ocular melanoma.