Finally, we investigated the relation between TMEM16A and tumor proliferation and metastasis related molecules, including KRAS/NRAS/BRAF mutations status, and expression of known proteins involved in CRC (Braf, CDX2, EGFR, p53, Ki67, CD34, MLH1, MSH2, MSH6, and PMS2). This evidence concerns the gene ANO1 and colorectal carcinoma.