In addition to MMRd status, PD-L1 expression was associated with tumor differentiation in ECs, with high-grade tumors had significantly higher frequency of positive PD-L1 expression in both TCs (grade 3 vs grade 2: p = 0.0264; grade 3 vs grade 1: p = 0.0054) and ICs (grade 3 vs grade 2: p = 0.0015; grade 3 vs grade 1: p = 0.0008) compared to tumors with lower grades (Figures 2E, F). This evidence concerns the gene CD274 and neoplasm.