MTOR and neoplasm: However, more studies are still needed to further explore the tumor suppressor role of NRBP2 in the malignant progression of BC, such as the specific localization of NRBP2 in BC cells, the possibility of NRBP2 translocation to the nucleus, and the specific mechanism by which NRBP2 regulates the AMPK/mTOR pathway, among other processes.