Most tumors are often accompanied by abnormal activation or inhibition of various molecules and signaling pathways during their development and metastasis (22, 23), and AMPK/mTOR signaling is one of the irreplaceable pathways in tumor cells (24) because it not only regulates the level of intracellular autophagy (25) but also regulates biological processes such as the proliferation, apoptosis and invasion of tumor cells (25). The gene discussed is MTOR; the disease is neoplasm.