Moreover, we also examined previously reported SPTCL-related genes (10) and found a group of genes significantly differentially expressed in the SPTCL cells (i.e., APOBEC3G, CCL4, CCL5, CXCL10, CXCR3, FASLG, GBP5, IFNG, IKZF3, KLRD1, PRF1, and TNFRSF9 (Padj < 1 x 10-10; Supplementary Figure S11). The gene discussed is PRF1; the disease is subcutaneous panniculitis-like T-cell lymphoma.