We also checked the expression of genes (HAVCR2, TNF, IL2, CXCL10, IL18, and IL2RA/CD25) in our scRNA-seq data for malignant and normal T cells and found regular expression of HAVCR2 and CXCL10 and low expression of TNF, IL2, IL18, and IL2RA(CD25) in the SPTCL malignant cells (Supplementary Figure S5) compared with normal T cells, suggesting the difference between HAVCR2-wild-type and mutant SPTCL patients. The gene discussed is IL2; the disease is subcutaneous panniculitis-like T-cell lymphoma.