Okubo et al. (57) developed a xenograft mouse model using a human tongue squamous cell carcinoma (SCC) cell line and reported that the irradiation-induced tumor infiltration by CD11b+ bone marrow-derived cells that acquired an M2-like phenotype, promoted tumor re-vascularization, progression and recurrence after radiotherapy. The gene discussed is ITGAM; the disease is neoplasm.