Nielsen et al. (40) showed that CD20+ tumor-infiltrating lymphocytes similarly had an atypical memory phenotype (CD27−) in ovarian cancer and that the cells highly expressed antigen-presenting molecules (MHC-I, MHC-II, CD40, CD80, CD86) and co localized with CD8+ T cells, suggesting that it presented tumor antigens and activated tumor killer T cells, resulting in tumor suppression. The gene discussed is CD40; the disease is ovarian carcinoma.