The results of GSEA analysis showed that samples with FAT3 mutation enriched in “ERBB2 Breast Preneoplastic UP”, “Kras Oncogenic Signature”, “Malignant Skin Tumor DN”, “MCV6 LCP With H3K27ME3”, and “MET Signaling” (Figure 4). The gene discussed is ERBB2; the disease is skin neoplasm.