HOTAIRM1 and neoplasm: To further investigate the effect of HOTAIRM1 overexpression of transformed fibroblasts on tumorigenicity of GSCs, in vivo combined inoculation of GSCs-SU3 and HOTAIRM1 upregulated t-FB1/2 cells was performed, tumor volume and weight were increased, compared with the control group (Supplementary Figures 2G–L).