MRC1 and colorectal cancer: Cellular uptake of the radiolabelled complex [111In][In-2]4+ (log P = –2.46 ± 0.26) was examined in three human colorectal cancer cell lines: DLD-1 and HCT-116, which are both MMR-deficient and hypermutated, and HT-29, which is MMR proficient and nonhypermutated (Table S2† and ref. 42).