It is shown that D-dimer and c-reactive protein levels are different in COVID patients who develop pulmonary embolism.49 An investigation hypothesized “the development of PTE in COVID-19 might be a pulmonary artery thrombosis due to severe lung inflammation and hypercoagulability rather than thromboembolism” for explaining pulmonary embolism in these patients.49 In contrast, another study declared that severe manifestations of COVID-19 is more associated with local thrombi in lungs rather than emboli.50 This evidence concerns the gene CRP and Thromboembolism.