Many studies have found that HOXB cluster members are involved in the tumorigenesis or progression of ovarian cancer, including HOXB2 (Yu and Pan, 2020), HOXB3 (Miller et al., 2018), HOXB4 (Li et al., 2018), HOXB7 (Chen et al., 2020), and HOXB8 (Stavnes et al., 2013). Here, HOXB4 is linked to ovarian cancer.