HLA-DPA1 and Graves disease: This patient also carries DRB1*15 and DPA1*03:01 HLA alleles, which were significantly associated with ADEM (Alves-Leon et al., 2009), and haplotype DRB3*02:02-DQA1*05:01, associated with Graves' disease (Chen et al., 2000; Table 3, Supplementary Table 2).