TFPI2 and central nervous system cancer: In high-grade gliomas and glioblastoma cell lines, there was a significantly positive correlation between AC003092.1 and TFPI2 (high-grade gliomas: Spearman rank correlation coefficient r = 0.8614, p < 0.001; glioblastoma cell lines: Spearman rank correlation coefficient r = 0.8200, p < 0.05) (Figures 5A,B and Supplementary Figure 1).