Subsequently, Goldstein and co-workers used PU-H71 and tumor-enriched HSP90 (teHSP90) complexes derived from DLBCL cell lines to show that LYN, SYK, BTK and phospholipase C γ 2(PLCγ2) are dependent on teHSP90 (110). This evidence concerns the gene HSP90AB1 and diffuse large B-cell lymphoma.