NFKB1 and lymphoma: One of the major hallmark of lymphoma is represented by the deregulated critical signaling pathways including NF-kB, JAK-STAT, BCR signaling, PI3K/AKT, MAPK/ERK and apoptosis signaling pathways (82, 85–88, 190).Noticeably, specific members of HSP families, in particular, HSP90 showed to interfere with all these signaling cascades (83, 89, 103).