Moreover, SLURP-1 was detected in skin nerve fibers shortly after its first description in 1999 (44, 85, 86) and close contacts of calcitonine gene related peptide+ cholinergic nerve fibers with Chrna7+ MC were reported in a food allergy model, in which Chrna7 agonists attenuated MC hyperplasia and allergic inflammation (87). Here, SLURP1 is linked to food allergy.