CRP: 10 mg/L  ESR: 140.5 mm/h  MRI brain: Mild cerebral atrophy with dilated lateral ventricles and cisterns  IgG: 1,472 mg/dL  IgA: 124 mg/dL  IgM: 181 mg/dL  IgE: 785 mg/dL. Here, IGHE is linked to Cerebral atrophy.