A24 is a neutralizing murine anti-human TfR1 IgG2b antibody that has been shown to inhibit the in vitro proliferation and induce apoptosis in adult T-cell leukemia/lymphoma (ATLL), acute myeloid leukemia (AML), and mantle cell lymphoma (MCL) cells (94, 119, 128). This evidence concerns the gene TFRC and acute myeloid leukemia.