We found that BANK1 expression is down-regulated, after CD40 activation (GSE54017, p < 0.001), in B cells from CLL patients (GSE22529, p < 0.001), as well as in plasma cells (GSE6691, p < 0.001) (Figures 2D–F). This evidence concerns the gene BANK1 and B-cell chronic lymphocytic leukemia.