In the present study, using voxel-wise analysis, we aim to investigate the association between the spatial locations of pDGs and the expression of immune checkpoint molecules including B7-H3, CD47, and PD-L1, as well as the tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs), when compared to the adult DGs. Here, CD274 is linked to neoplasm.