A 16 mmol/l of serum anion gap is just slightly above the normal range and this is an important issue because such a disturbance along with the negative urine anion gap would indicate that kidney is still able to excrete ammonium, and the cause of metabolic acidosis is mainly ascribed to the severe loss of bicarbonates related to VIP-mediated secretory diarrhea. Here, VIP is linked to Acidosis.