The differential-diagnosis of Fanconi syndrome itself is broad and includes (non-exhaustively) mitochondrial respiratory chain diseases, metal intoxications, Wilson’s disease, cystinosis, multiple myeloma [especially when involving light chains (34)], Sjögren’s disease, medications like ifosfamide or tenofovir, genetics forms of renal tubular acidose, Dent’s disease and Lowe’s oculocerebrorenal syndrome (from OCRL1 or CLCN5 mutations). The gene discussed is CLCN5; the disease is Fanconi renotubular syndrome.