PHOX2B and sudden infant death syndrome: In order to evaluate the effects of the PHOX2B c.*161G>A 3′UTR variant, a 219-bp region amplified from a SIDS patient heterozygous at this locus was cloned in the pmiRGLo reporter plasmid downstream the firefly luciferase gene and the construct thus obtained transfected in the IMR32 human neuroblastoma cell line.