IL17A and periodontal disorder: Patients with congenital neutrophil deficiencies always have clinical manifestations of severe or aggressive periodontal diseases accompanied with dysregulated IL-17/Th17 immune response (Amulic et al., 2012; Hajishengallis et al., 2014), (Moutsopoulos et al., 2015), which implicates immunoregulatory role of neutrophils in oral cavity (Kruger et al., 2015).