Results of other study conducted by Weber et al. show higher expression of Gal-3 in radicular cysts compared to apical granulomas and lower expression in dentigerous cysts, non inflammatory cause (de Moraes et al., 2014) developmental odontogenic cysts (Wright et al., 2014), than in both periapical pathologies (Weber et al., 2019), while Brito et al. reported no significant differences in Gal-3 immunoexpression in periapical granulomas, radicular cysts, and residual radicular cysts (Brito et al., 2018). This evidence concerns the gene LGALS3 and periapical granuloma.