AKT1 and ovarian carcinoma: Knockdown of WTAP in ovarian cancer cells decreased expression of several MAPK proteins such as p-ERK, ERK, p-JNK, JNK, p38 and p-p38 as well as AKT pathway proteins (p-AKT, AKT) indicating the association of these two pathways with WTAP in ovarian cancer [45].