PIMS-TS children had significantly elevated levels of cytokines, IFNγ, IL-2, TNFα, IL-1α, IFNα, IFNβ, IL-6, IL-17A, GM-CSF, IL-10, IL-33 and IL-Ra in comparison to COVID-19, seropositive and control children. Here, IL33 is linked to COVID-19.